Exit the airport and follow signs for FL-60 W toward St. Petersburg
Merge onto I-275 S toward St. Petersburg
Take Exit 26 – 54th Ave S and turn right
Turn right onto Park St N
Turn left onto 74th Ave N
Turn right onto Conch Blvd and enter Seminole Isle
Continue to 7343 Conch Blvd
Uber/Lyft: ~$30–$55